I-Chlormadinone acetate (CMA) iyi-agonist enamandla ye-progesterone receptor (PR), umphikisi oyingxenye ye-androgen receptor (AR) kanye nomphikisi obuthakathaka we-glucocorticoid receptor (GR).I-Chlormadinone ibophezela kuma-PRs, okwenza ukuvezwa kwezakhi zofuzo ezisabelayo ze-progesterone.
Igama Lomkhiqizo | I-Chlormadinone acetate |
Igama Lekhemikhali | 17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione |
Elinye Igama | I-Clormadinoneacetate;i-chloromadinone17-acetate;6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione;17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione,6-Chloro- 6-dehydro-17α-acetoxyprogesterone,Gestafortin,Matrol,Menstridyl,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate;17-alpha-acetoxy-;ChChemicalbooklormadinoneacetate,17α-Acetate -chloro-4,6-pregnadiene-3,20-dione,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate,6-Chloro-6-dehydro-17α-acetoxyprogesterone,Gestafortin ,Matrol,Abesilisa;(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12 ,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylacetate |
Inombolo ye-CAS | 302-22-7 |
I-Molecular Formula | I-C23H29ClO4 |
Isisindo Sefomula | 404.93 |
Ukubukeka | I-Crystalline Powder Emhlophe Kuya Kuphuzi;Ayinaphunga, ayinambitheki |
Isivivinyo | 98.0% iminithi |
I-Melting Point | 212°C |
Iphuzu elibilayo | 512.5±50.0 °C |
I-Absorption Peak | 1.1345 g/cm3 |
Iphakheji | 20kg/bag/drum, 25kg/bag/drum, noma njengoba ubufuna |
Isitoreji | Gcina isitsha sivalwe ngokuqinile endaweni eyomile nepholile.Ungachazi elangeni eliqondile. |
I-COA ne-MSDS | Iyatholakala |
Isicelo | Ngenhloso yocwaningo |
TEST | IMIGOMO YOKWAMUKELA | IMIPHUMELA |
Ukuhlonza | I-TLC | Okuhle |
I-spectrum ye-UV | Okuhle | |
I-spectrum ye-IR | Okuhle | |
Izici | I-crystalline powder emhlophe noma ephuzi | vumelana |
Iphoyinti lokuncibilika | 211 ~ 215℃ | 211 ~ 214 ℃ |
Ukujikeleza kwe-optical okuqondile | ﹣10° ~﹣14° | ﹣12.5° |
Ukuncibilika | Incibilika ngokukhululeka ku-chloroform, inyibilika ku-acetonitrile, incibilika kancane ku-ethanol ne-ether futhi ayincibiliki cishe emanzini. | vumelana |
Ukulahlekelwa ekomisweni | ≤0.5% | 0.21% |
Izinsalela ekushiseni | ≤0.1% | 0.04% |
Amanye ama-steroid | ≤1.0% | 0.59% |
Izinsimbi ezinzima | ≤20ppm | Dlula |
I-Arsenic | ≤2ppm | Dlula |
Isivivinyo | ≥98.0% | 98.9% |
Ama-Residual solverts(GC) | I-acetone ≤5000ppm I-Methanol≤3000ppm I-Pyridine≤200ppm | Dlula Dlula Dlula |
I-Chlormadinone acetate imithi ye-progestin kanye ne-antiandrogen esetshenziswa kumaphilisi okulawula ukuzalwa ukuvimbela ukukhulelwa, njengengxenye yokwelashwa kwe-hormone ye-menopausal, ekwelapheni izifo zabesifazane, kanye nokwelapha izimo ezincike ku-androgen njenge-prostate ekhulisiwe kanye nomdlavuza wendlala yesinye. amadoda kanye nezinduna kanye hirsutism kwabesifazane.
Kufanele ngithathe kanjani i-Chlormadinone acetate?
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Isikhathi esiholayo
≤100kg: zingakapheli izinsuku ezintathu zokusebenza ngemuva kokutholwa kwenkokhelo.
>100kg: isonto elilodwa
Isampula
Iyatholakala.
Iphakheji
20kg/bag/drum, 25kg/bag/drum
noma njengoba ubudinga.
Isitoreji
Gcina isitsha sivalwe ngokuqinile endaweni eyomile nepholile.
Ungachazi elangeni eliqondile.