I-API Obeticholic acid CAS 459789-99-2 ye-biliary cholangitis

Incazelo emfushane:

I-Obeticholic acid isetshenziswa iyodwa noma ekwelapheni okuhlangene kwesifo esithile sesibindi (primary biliary cholangitis-PBC).

Othintana naye: Erica Zheng

Email: erica@zhuoerchem.com

Ucingo: +86 21 2097 0332

Isixuku: +86 177 1767 9251

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Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

I-Obeticholic acid isetshenziswa iyodwa noma ekwelapheni okuhlangene kwesifo esithile sesibindi (primary biliary cholangitis-PBC).

Ukucaciswa:

Igama Lomkhiqizo	I-Obeticholic Acid
Igama Lekhemikhali	6-Ethylchenodeoxycholic acid
Elinye Igama	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph4 Acid7,6(INT) -ECDCA)
Inombolo ye-CAS	459789-99-2
I-Molecular Formula	I-C26H44O4
Isisindo Sefomula	420.63
Ukubukeka	Impushana emhlophe
Isivivinyo	99.0% iminithi
Ukuminyana	1.091 g/cm3
I-Melting Point	108-110 °C
Iphuzu elibilayo	562.9±25.0 °C
Iphakheji	20kg/bag/drum, 25kg/bag/drum, noma njengoba ubufuna
Isitoreji	Gcina isitsha sivalwe ngokuqinile endaweni eyomile nepholile.Ungachazi elangeni eliqondile.
I-COA ne-MSDS	Iyatholakala

Ukusetshenziswa

I-Obeticholic acid iyi-dihydroxy-5beta-cholanic acid eyi-chenodeoxycholic acid ephethe i-ethyl eyengeziwe esikhundleni se-6alpha-position.I-semi-synthetic bile acid esebenza njenge-farnesoid X receptor agonist futhi isetshenziselwa ukwelapha i-primary biliary cholangitis.Inendima njenge-farnesoid X receptor agonist kanye ne-hepatoprotective agent.Kuyi-dihydroxy-5beta-cholanic acid, i-3alpha-hydroxy steroid kanye ne-7alpha-hydroxy steroid.Itholakala ku-chenodeoxycholic acid.
I-Obeticholic acid (OCA) i-synthetically modified bile acid kanye ne-agonist enamandla ye-farnesoid X nuclear receptor (FXR) esetshenziselwa ukwelapha izifo zesibindi kuhlanganise ne-primary biliary cholangitis.