I-API Pitavastatin Calcium CAS 147526-32-7

Incazelo emfushane:

I-Pitavastatin isetshenziswa kanye nokudla okufanele ukusiza ukwehlisa i-cholesterol “embi” namafutha (afana ne-LDL, triglycerides) futhi kukhuphule i-cholesterol “enhle” (HDL) egazini.

Othintana naye: Erica Zheng

Email: erica@zhuoerchem.com

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Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

I-Pitavastatin isetshenziswa kanye nokudla okufanele ukusiza ukwehlisa i-cholesterol "embi" namafutha (afana ne-LDL, triglycerides) futhi ikhuphule i-cholesterol "enhle" (HDL) egazini.

Ukucaciswa:

Igama Lomkhiqizo	I-Pitavastatin calcium
Igama Lekhemikhali	calcium;(E,3R,5S) -7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
Elinye Igama	I-PitavasttinCalcium;PitavastatinCalcium/NK-104;(+)-Monocalciunbis{(3r,5s,6e)-7-[2-cyclopropyl-4-(4-fluorophenyl-3-quinolyl]-3,5-dihydroxy-6-heptenotate };PitavastatincalciuM(Livalo);I-Calcium(3R,5S,E)-7-(2-cyclopropyl-Chemicalbook4-(4-fluorophenyl)-quinolin-3-yl)-3,5-dihydroxyhept-6-enoate;(3R ,5S,6E) -7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoicacid,calciumsalt(2:1);NK-104Calcium;PitavastatinCalciuMDISIYAQHUBEKA
Inombolo ye-CAS	147526-32-7
I-Molecular Formula	I-C25H26CaFNO4
Isisindo Sefomula	463.56
Ukubukeka	Okuqinile
Isivivinyo	98.0% iminithi
Iphakheji	20kg/bag/drum, 25kg/bag/drum, noma njengoba ubufuna
Isitoreji	Gcina isitsha sivalwe ngokuqinile endaweni eyomile nepholile.Ungachazi elangeni eliqondile.
I-COA ne-MSDS	Iyatholakala

Ukusetshenziswa

I-Pitavastatin Calcium iyi-inhibitor encintisanayo ye-enzyme HMGCR (HMG-CoA reductase) iphumela ekuncipheni kwe-LDL cholesterol synthesis.Olunye ucwaningo lubonisa ukuthi i-pitavastatin ingacindezela ukukhiqizwa komoyampilo kumaseli e-endothelial ngokuvimbela i-NADPH oxidase.Ngaphezu kwalokho, i-pitavastatin yehlisa ukuvezwa kwe-eNOS mRNA ngenkathi ikhulisa impendulo encike ku-NO egqugquzelwa i-acetylcholine kanye ne-calcium ionophore, A23187.Ngaphezu kwalokho, i-pitavastatin ivimbela ukulawulwa kwe-conductance calcium-activated potassium channels ngokwehlisa amazinga e-cholesterol kumaseli.