I-Olivetoliyinhlanganisela eye yathola ukunakwa okukhulu eminyakeni yamuva ngenxa yezakhiwo zayo zokwelapha ezingaba khona.Lesi sihloko sihlose ukuhlola imithombo yemvelo ye-olivetol futhi sicacise ukubaluleka kwayo emikhakheni ehlukahlukene.
I-Olivetol, eyaziwa nangokuthi i-5-pentylresorcinol, iyinhlanganisela ye-phenolic etholakala ezitshalweni ezithile.Isuselwa ku-phytocannabinoid biosynthesis futhi iyisandulela kuma-cannabinoids ahlukahlukene, kufaka phakathi i-cannabidiol (CBD).Le nhlanganisela idlala indima ebalulekile ekukhiqizeni ama-phytocannabinoids, aziwa ngemiphumela yawo yokwelapha.
Omunye wemithombo yemvelo eyinhloko ye-olivetol yi-hemp, eyaziwa ngokuthi i-hemp.Lesi sitshalo sicebile kuma-phytocannabinoids, futhi i-olivetol ibandakanyeka ku-biosynthesis yayo.Abacwaningi bathole ukuthi i-Olivetol iyingxenye ebalulekile yokuguqulwa kwe-gernyl diphosphate (GPP) ibe yi-CBD ngaphakathi kwesitshalo se-cannabis.
Ngaphezu kwe-cannabis,i-olivetoliyatholakala nakwezinye izinhlobo zezitshalo zomndeni wakwaCannabaceae.Isibonelo, ama-hops (ngokuvamile abizwa ngokuthi ama-hops) aqukethe amafutha omnqumo ezimbalini zawo.AmaHops aziwa ngokuyinhloko ngokusetshenziswa kwawo ekwenzeni ubhiya, kodwa futhi anezindawo zokwelapha.Amafutha omnqumo asiza ukukhiqiza izinhlanganisela eziyingqayizivele kuma-hops, njenge-xanthohumol, enamandla okulwa nomdlavuza kanye ne-antioxidant.Ucwaningo ngama-hops kanyei-olivetoliyaqhubeka ukuqonda ngokugcwele izicelo zabo zokwelapha.
Ngaphezu kwalokho,i-olivetolingakhiqizwa ngokwenziwa elabhorethri.Ukukhiqizwa kokwenziwa kwei-olivetolivumela abacwaningi ukuthi bahlole izicelo zayo ezingase zibe khona futhi benze okuphumayo okungenzeka kuthuthukise izakhiwo zokwelapha.Zokwenziwai-olivetolisetshenziselwe ukutadisha indima yayo njengesandulela ezindleleni ezihlukahlukene ze-cannabinoid synthesis, okufaka isandla ekuqondeni kwe-phytocannabinoid biosynthesis.
Imithombo yemvelo yei-olivetolbaye baheha isithakazelo emikhakheni yezokwelapha nemithi ngenxa yamandla e-cannabinoids ekwelapheni izimo zezempilo ezihlukahlukene.Ama-cannabinoids atholakala kuwoi-olivetol, njenge-CBD, ibonise isithembiso ekwelapheni ubuhlungu, isithuthwane, ukukhathazeka, nokuvuvukala.Amafutha omnqumo amaningi ngokwemvelo atholakala ku-hemp kanye nama-hops ahlinzeka ngensiza eqhubekayo yokukhipha kanye nokukhiqizwa kwalezi zinhlanganisela zokwelapha.
Ukwenziwa kube semthethweni kanye nokuqedwa kwe-cannabis kwezinye izifunda eminyakeni yamuva nje kunikeze amathuba ocwaningo olwengeziwe mayelana nezicelo zezokwelapha.i-olivetol- ama-compounds atholakalayo.Ososayensi bahlola izindlela zokwandisa ukukhiqizwa kukawoyela wezitshalo ngokuguqula izakhi zofuzo kanye nezinqubo zokukhula ezithuthukisiwe.Lolu cwaningo luhlose ukuthuthukisa izinhlobo ezithuthukisiwe ze-cannabis noma eminye imithombo yezitshalo ukunika amandla ukukhiqizwa okungabizi nokusimeme kwama-cannabinoids okwelapha.
Ngokufigqiwe,i-olivetoliyinhlanganisela ebalulekile ku-biosynthesis ye-phytocannabinoids, kuhlanganise ne-CBD.Imithombo yayo yemvelo ihlanganisa insangu nama-hops, womabili ahlolisisiwe ukuze asebenzise izindlela zokwelapha ezingase zibe khona.Ucwaningo oluqhubekayo nokuqonda kwei-olivetolkanye nokuphuma kwayo kunesithembiso esikhulu sokwakhiwa kwemithi emisha nezinketho zokwelapha zezimo zezempilo ezihlukahlukene.Njengoba isayensi iqhubeka nokuthuthuka, kubalulekile ukuhlola izinzuzo ezingaba khona kanye nezinkinga zokusebenzisai-olivetolkanye nezinhlanganisela ezihlobene kwezokwelapha futhi uqinisekise ukuthi lezi zinzuzo zisetshenziswa ngendlela ephephile nenesibopho.
Isikhathi sokuthumela: Nov-13-2023