Pregabalin CAS 148553-50-8 Featured Image

IPregabalin CAS 148553-50-8

Incazelo emfushane:

I-Pregabalin yisidakamizwa esisha se-antiepileptic, esine-γ-amino butyric acid isakhiwo esakhiweni sayo samangqamuzana, esinemiphumela ye-anticonvulsant.

Thumela i-imeyili kithi

Imininingwane yomkhiqizo

Amathegi womkhiqizo

Incazelo

I-Pregabalin yisidakamizwa esisha se-antiepileptic, esine-γ-amino butyric acid isakhiwo esakhiweni sayo samangqamuzana, esinemiphumela ye-anticonvulsant.

Ukucaciswa:

Igama lomkhiqizo	I-Pregabalin
CAS Cha	148553-50-8
Ukuhlanzeka	99%
Ifomula Yamamolekhula	C8H17NO2
Isisindo Semolekyuli	159.23
Iphuzu lokuncibilika	Ngo-194-196 ° C
Ubuningi	0.997 ± 0.06 g / cm3 (Kubikezelwe)
Ukubukeka	I-crystal powder emhlophe
Ibanga	Ibanga lezemithi
Isigaba	Isithako Esisebenzayo Semithi (API)
Isigaba Sezidakamizwa	I-Anticonvulsant - Ama-GABA Analogs · Ama-Agents We-Diabetic Peripheral Neuropathy · Ama-Fibromyalgia Agents - Ama-GABA Analogs · Ukwelashwa Kwezinhlungu Ze-Neuropathic · Ama-Postherpetic Neuralgia Agents
Umkhiqizo	SHXLCHEM

Ishidi Lezobuchwepheshe / i-TDS:

Incazelo	Mhlophe ukucisha impuphu emhlophe yekristalu
Ukuphendula kombala okwehliswayo	Isixazululo se-Ninhydrin sokuphendula ngokuluhlaza okwesibhakabhaka
Ukuvezwa nge-IR	I-spectrum ye-IR iyahambisana nezinga elijwayelekile lesethenjwa
Ukuncibilika	Kuncibilika kancane emanzini ngokubukeka
Ukujikeleza okukhethekile okubonakalayo	Phakathi kuka- + 8.5 ° kuye ku- + 12.0 °
Into ehlobene yi-HPLC (-) Amide	Hhayi ngaphezu kuka-0.15%
4E	Hhayi ngaphezu kuka-0.15%
5E	Hhayi ngaphezu kuka-0.15%
I-Lactum	Hhayi ngaphezu kuka-0.15%
Ukungcola okungaziwa	Hhayi ngaphezu kuka-0.15%
Ukungcola okuphelele	Hhayi ngaphezu kuka-0.15%
Izinsimbi ezisindayo	Hhayi ngaphezulu kuka-200ppm
Umlotha oshubile	Hhayi ngaphezu kuka-0.1% w / w
Ukulahlekelwa kokomiswa	Ayikho ngaphezu kuka-0.5% w / w
I-Methanol	Hhayi ngaphezulu kuka-3000ppm
Toluene	Hhayi ngaphezulu kuka-890ppm
I-N-butanol	Hhayi ngaphezulu kuka-5000ppm
I-ethyl acetate	Hhayi ngaphezulu kuka-5000ppm
IChloroform	Hhayi ngaphezulu kuka-60ppm
I-N-hexane	Hhayi ngaphezulu kuka-290ppm
Ubumsulwa be-Emantiomeric ngokuqukethwe kwe-HPLC R-Pregabalin	Ayikho ngaphezu kwe-0.15% yendawo yeR-Pregabalin
Ukuncwaninga izinsimbi okwenziwe yi-HPLC (ngesisekelo esomile)	Hhayi ngaphezulu kuka-98.0 w / w futhi Angabi ngaphezu kuka-102.0% w / w

Isicelo

I-Pregabalin iyi-Active Pharmaceutical Ingredient (i-API), evame ukusetshenziselwa ukubulala ubuhlungu obudalwa ukulimala kwemizwa ngenxa yesifo sikashukela, isifo se-shingles (herpes zoster), noma ukulimala komgogodla. I-Pregabalin ibuye isetshenziselwe ukwelapha ubuhlungu kubantu abane-fibromyalgia. Ibuye isetshenziswe neminye imithi yokwelapha izinhlobo ezithile zokuquleka (ukugxila okugxile).